Genome-wide association of early-onset myocardial infarction with common single nucleotide polymorphisms, common copy number variants, and rare copy number variants. Nat Genet 2009;41: 334-341.

Kathiresan S, Voight BF, Purcell S, Musunuru K, et al. PMID: 19198609 (cited by 480).

This is among the first published genome-wide association studies for the early-onset myocardial infarction (MI) phenotype.  We demonstrated that common DNA sequence variants at nine gene regions contribute to risk for MI, the leading cause of death in the U.S.

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